Unusual Intermolecular “Through-Space”JCouplings in P–Se Heterocycles

Pom1 gradient buffering through intermolecular auto-phosphorylation

Concentration gradients provide spatial information for tissue patterning and cell organization, and their robustness under natural fluctuations is an evolutionary advantage. In rod-shaped Schizosaccharomyces pombe cells, the DYRK-family kinase Pom1 gradients control cell division timing and placement. Upon dephosphorylation by a Tea4-phosphatase complex, Pom1 associates with the plasma membran...

Portal systemic encephalopathy (PSE).

Sixtynine cases of portal systemic encephalopathy (PSE) (45 cirrhosis, 24 hepatitis) were seen during 15 months. Coma due to acute viral hepatitis occurred in a younger age group as compared to cirrhosis. Upper gastrointestinal bleeding and hepatic necrosis were the main precipitating factors. Most of the patients were in grade Ill (37.6%) and IV (34.7%) coma when first seen. Blood ammonia nitr...

Synthesis of Medicinally Privileged Heterocycles through Dielectric Heating.

BACKGROUND Heterocyclic compounds are intriguing part of modern drug discovery research. Ecofriendly syntheses of heterocycles, following green techniques, are privileged routes to protect Mother nature. Microwave-assisted synthesis of chemical compounds is considered as a major greener pathway, both in academia and industry. METHODS A total of 106 publications (including a few authentic web ...

Does Nature Prefer Heterocycles?

Alkylation of Oxazolones and Related Heterocycles through an SN1 Reaction

[a] Department of Organic Chemistry, Universitat de Barcelona, C/ Martí i Franqués 1-11, 08028 Barcelona, Spain Fax: +34-93-3397878 E-mail: [email protected] [b] Departament de Cristalografia, Mineralogia i Dipòsits Minerals, Universitat de Barcelona, Martí i Franqués s/n, 08028 Barcelona, Spain [c] ICREA, Passeig Lluis Companys 23, 08010 Barcelona, Spain Supporting information for this arti...